Continuous protein recovery from whey using liquid-solid circulating fluidized bed ion-exchange extraction

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Abstract

A liquid-solid circulating fluidized bed (LSCFB) continuous ion-exchange extraction system has been investigated for total protein recovery from whey solutions under various operating conditions. The effectiveness of a dynamic seal was evaluated between the riser and the downcomer, and the best conditions for the establishment of this seal were established. Start-up studies indicated that the system is robust and stable. Under optimal conditions, a productivity of 8.2 g of total protein removed per hour per kilogram of resin was achieved with a protein removal efficiency of 78.4%. However, higher overall protein recovery of up to 90% was also achieved under other conditions, with lower protein concentration in the effluent and a lower overall productivity. © 2002 Wiley Periodicals, Inc.

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Lan, Q., Bassi, A., Zhu, J. X., & Margaritis, A. (2002). Continuous protein recovery from whey using liquid-solid circulating fluidized bed ion-exchange extraction. Biotechnology and Bioengineering, 78(2), 157–163. https://doi.org/10.1002/bit.10171

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