MICROENCAPSULATION OF FLAVONOIDS FROM GEDI LEAVES (Abelmoschus manihot L.) IN β-CYCLODEXTRIN USING COPRECIPITATION AND KNEADING METHODS

Abstract

The protection of active compounds such as flavonoids as candidate drug compounds has been the focus of several studies in recent years. This is due to the different physicochemical properties of flavonoids. Furthermore, the function of these flavonoid compounds can be maximized from the initial process of separating them from the plant of origin known as extraction. This study compared the effectiveness and efficiency of using microwave extraction and maceration of Gedi leaves (Abelmoschus manihot L.). Then, the extract was encapsulated to protect the unstable flavonoids. There were two methods to encapsulate the extract in this study. They were the coprecipitation and kneading methods. The result shows that microwave extraction assisted has higher product in less solvent and was time-consuming. The coprecipitation also shows better performance in encapsulating the extract. The calculation of the efficiency of encapsulation was done for 3 different volumes of both methods. The addition of 1 mL extract by coprecipitation showed approximately 92.12%. It was also supported by the data of FTIR and UV VIS.