N-nitropyridinium nitrate: An efficient nitrating agent for the synthesis of 2-[butyl(nitro)amino]ethyl nitrate (n-BuNENA)

Abstract

The present investigation focused on the synthesis of 2-[butyl(nitro) amino]ethyl nitrate (n-BuNENA), by the nitration of N-butylethanolamine. For this purpose, various nitrating agents were studied and N-nitropyridinium nitrate was found to be a good nitrating agent. Short reaction time, ease of handling, performance of the reaction in one step and good yield are the main aspects of the present method. It also lead to 75% yield, which is a higher yield than by other methods. The purity of the product was evaluated by HPLC analysis, and its identity was confirmed by IR and 1H NMR spectroscopy. Copyright