Intra-articular and circulating levels of type i and III collagen markers in inflammatory and degenerative joint disease

Abstract

In a chronic inflammatory disease as rheumatoid arthritis, the local processes in the affected tissues lead to destruction of the joint. When estimating the inflammatory activity in rheumatic joint diseases, a major problem is the rather unspecific and indirect character of the biochemical and the crude character of the clinical measures used. © 1995 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.