Statins and Risk of Diabetes

Abstract

Statins have a relevant role in decreasing cardiovascular mortality. Statins are effective in primary and secondary prevention. Recently, it has been suggested that statins may have a diabetogenic effect, because a moderate increase in the risk of newly developed diabetes mellitus was observed. The diabetogenic effect of statins is a group effect and it is dose-dependent, too. The effect of statins which lower the cardiovascular risk attenuates the risk of developing diabetes during statin therapy, too. Hence, statins remain the first line therapy of reaching LDL-cholesterol targets.