Purpose: Therapeutic efficacy and safety in infections due to multidrug-resistant bacteria can be improved by the clinical development of new compounds and devising new derivatives of already useful antibiotics. Due to a striking global increase in multidrug-resistant Gram-positive but even more Gram-negative organisms, new antibiotics are urgently needed. Methods: This paper provides a review of novel antibiotic compounds which are already in clinical development, mainly in phase III clinical trials. Conclusion: Each of these new trials increases the possibility of new antibiotics receiving approval.
CITATION STYLE
Draenert, R., Seybold, U., Grützner, E., & Bogner, J. R. (2015, April 1). Novel antibiotics: Are we still in the pre–post-antibiotic era? Infection. Urban und Vogel GmbH. https://doi.org/10.1007/s15010-015-0749-y
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