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Multicenter evaluation of the solana group a streptococcus assay: Comparison with culture

Journal of Clinical Microbiology (2016) 54(9) 2388-2390
DOI: 10.1128/JCM.01268-16
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Abstract

We compared group A Streptococcus (GAS) culture with a rapid helicase-dependent amplification (HDA) method using 1,082 throat swab specimens. The HDA method demonstrated 98.2% sensitivity and 97.2% specificity. GAS prevalence by culture was 20.7%, and it was 22.6% using the HDA method. In 35 min, the HDA method provided rapid, sensitive GAS detection, making culture confirmation unnecessary.

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Uphoff, T. S., Buchan, B. W., Ledeboer, N. A., Granato, P. A., Daly, J. A., & Marti, T. N. (2016). Multicenter evaluation of the solana group a streptococcus assay: Comparison with culture. Journal of Clinical Microbiology, 54(9), 2388–2390. https://doi.org/10.1128/JCM.01268-16

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