Voltametric behavior of noradrenaline at 2-mercaptoethanol self-assembled monolayer modified gold electrode and its analytical application

Abstract

2-Mercaptoethanol self-assembled monolayer (ME/Au SAMs) was prepared on a gold electrode. The ME/Au SAMs was characterized by using ATR-FTIR and dynamic contact angle measurements. The electrochemical behaviors of noradrenaline (NE) on the ME/Au SAMs were studied in BR buffer solution. The modified electrode accelerated electron transfer rate of the redox of NE and showed an excellent eletrocatalytic activity. The diffusion coefficient (D) of NE was obtained to be 4.3×10-8 cm2 s-1. The catalytic current increased linearly with the concentration of NE in the range of 2.0× 10-6 -1.0×10-3 M by square wave voltammetry response. The modified electrode could eliminate the interference of ascorbic acid (AA) at 40-fold concentration of NE and could be satisfactorily used for the determination of NE in the drug injection. © 2003 by MDPI.