Association of serum cytokines levels, interleukin 10 -1082G/A and interferon-γ +874T/A polymorphisms with atopic asthma children from Saudi Arabia

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Abstract

The aim of this study was to clarify the role of IL-4, IL-10, IL-13 and interferon (IFN) -γ levels in atopic asthma patients by studying the relation between their serum levels and severity of the disease. The effect of IL-10 -1082G/A and IFN-γ +874T/A SNPs was also studied. The study included 200 atopic children with asthma and 50 age- and gender matched healthy children as controls. The levels of both IL-4 and IL-13 were significantly (. p

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Hussein, Y. M., Alzahrani, S. S., Alharthi, A. A., Ghonaim, M. M., Alhazmi, A. S., Eed, E. M., & Shalaby, S. M. (2014). Association of serum cytokines levels, interleukin 10 -1082G/A and interferon-γ +874T/A polymorphisms with atopic asthma children from Saudi Arabia. Cellular Immunology, 289(1–2), 21–26. https://doi.org/10.1016/j.cellimm.2014.03.006

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