Dietary habits of pregnant women in Bulgaria

Abstract

might be more beneficial than HE intervention for reducing maternal insulin resistance. Key messages: In women homozygous for the risk allele of MTNR1B rs10830962, risk of gestational diabetes was increased. For these women, PA intervention might be more beneficial than HE intervention for reducing maternal insulin resistance. Abstract citation ID: ckac130.241 Introduction: Coronavirus disease (COVID-19) has affected many pregnant women worldwide. Pregnant women with COVID-19 infection belong to a vulnerable group with concerns about the effect of the disease on maternal and neonatal health. Objectives: To assess association of COVID-19 on maternal and neonatal outcomes in Latvia. Methods: Data source was Medical Birth Register. A total of 17206 birth data for 2021 were included in the data analysis. Results: 2.1% (n = 358) women with COVID-19 (U07.1; U07.2) during pregnancy or delivery. COVID-19 infection was related to the following conditions during pregnancy-gestation diabetes (10.6% to 4.6%; p < 0.001); placental abruption (1.7% to 0.6%; p < 0.05). Birth outcomes for COVID-19 infected women showed that infection has led to the increased caesarean section (27.7% to 22.0%; p < 0.01), preterm birth (12.8% to 5.3%; p < 0.001); low birth weight 2499g rate (10.1% to 3.9%; p < 0.001); stillbirths (2.8% to 0.4%; p < 0.001) and newborn infections specific to the perinatal period (P35-P39) (9.5% to 5.2%; p < 0.05). Increased BMI (8.9% to 6.8%), fetal distress (3.9% to 2.4%); preeclampsia, eclampsia (3.2% to 2.1%), hypertension (2.8% to 2.0%), gestational hypertension (5.0% to 3.8%) more frequently were observed among COVID-19 infected patients but the difference was not statistically significant. COVID-19 associated with higher odds (adjusted by mother age, multiple births, gestational age, mode of delivery) of gestational diabetes (ORadj 2.3; 95%CI 1.7-3.4; p < 0.001), newborn infections specific to the perinatal period (ORadj 1.7; 95%CI 1.2-2.4; p < 0.01) and stillbirth (ORadj 4.0; 95%CI 1.9-8.2; p < 0.001). Conclusions: COVID-19 during pregnancy is associated with higher risk of adverse maternal and perinatal outcomes. The study results of short-term pregnancy outcomes show importance of implementation of all recommended COVID-19 prophylactic measures by public health specialists and clinicians during antenatal care. Key messages: COVID-19 during pregnancy is associated with higher risk of adverse maternal and perinatal outcomes. Study results of short-term pregnancy outcomes show importance of implementation of all recommended COVID-19 prophylactic measures by public health specialists and clinicians during antenatal care.