Comparative study of vitrectomy for dropped nucleus with and without the use of perfluorocarbon liquid. Clinical, electrophysiological and visual field outcomes

Abstract

Purpose: To compare pars plana vitrectomy for dropped nucleus with and without perfluorocarbon liquid. Methods: 24 eyes with dropped nucleus were randomized to undergo PPV with perfluorodecalin, (study, n=12) and without it (control, n=12). Visual acuity, IOP, visual evoked response and electroretinography were noted at study entry and up to 3 months after PPV. Humphrey perimetry was done at 3 months. Results: Final visual acuity was >20/60 in 75% of study eyes and 41.6% of controls. The two groups were statistically comparable with regard to the above parameters before PPV and during follow-up. The timing of vitrectomy did not significantly influence the final visual acuity. A higher rate of complications was seen in the control group. Conclusions: Perfluorodecalin facilitated the procedure and possibly minimized complications, and was found to be safe for intraoperative use in terms of recovery of visual acuity, stable ERG and VER, and normal visual fields.