Production route analysis of a therapeutic radionuclide 177Lu

Abstract

177Lu is used in medical research for various radiotheragnostic applications in nuclear medicine because of its various isotope properties. In this paper, we calculated the cross sections and production yields of the Lu isotope from different reactions X+176,174Lu and X+176Lu in energy levels from 0.001 to 100 MeV by using TALYS-1.96 and EMPIRE-3.2.2. Although n, d, and t reactions show an outstanding cross-section performance, α and t reactions show very impactful integral yield data. For the potential outcomes, these estimates are analyzed by comparing them to TENDL-2019 and EMPIRE-3.2.2.