New pyridine-containing non-cyclic and macrocyclic Schiff bases: Synthesis and interferon-inducing activity

Abstract

A series of new Schiff bases containing the Hantzsch pyridine skeleton has been synthesized by reaction of an appropriate aldehyde with 2,6-dimethyl-3,5-pyridinedicarboxhydrazide. The structure of the final products, which was highly dependent on the nature of the starting aldehyde, could readily be ascertained by their spectral data. 2,6- Dimethyl-3,5- pyridinedicarboxhydrazide itself and some of its derivatives emerged as potential interferon inducers.