Abstract
Ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br) efficiently accelerates Michael addition of pyrimidine and purine nucleobases to α,β-unsaturated esters in the presence of catalytic amount of Cs 2CO3 under microwave irradiation to give carboacyclic nucleosides in good to high yields and short reaction times. © ARKAT USA, Inc.
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Zare, A., Hasaninejad, A., Safinejad, R., Moosavi-Zare, A. R., Khalafi-Nezhad, A., Beyzavi, M. H., … Kazerooni-Mojarrad, P. (2008). Ionic liquid-accelerated Michael addition of pyrimidine and purine nucleobases to α,β-unsaturated esters: A rapid approach to carboacyclic nucleosides synthesis. Arkivoc, 2008(16), 61–74. https://doi.org/10.3998/ark.5550190.0009.g06
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