Aspergillus oryzae laea regulates kojic acid synthesis genes

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Abstract

Kojic acid synthesis genes regulation was investigated in Aspergillus oryzae. Our results indicate that kojic acid production was lost in the laeA disruption strain, but was recovered in the LaeA complement strain. Realtime PCR also confirmed that expression of kojic acid biosynthesis genes decreased in the laeA disruption strain, indicating that these genes are under the control of LaeA.

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Oda, K., Kobayashi, A., Ohashi, S., & Sano, M. (2011). Aspergillus oryzae laea regulates kojic acid synthesis genes. Bioscience, Biotechnology and Biochemistry, 75(9), 1832–1834. https://doi.org/10.1271/bbb.110235

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