Synthesis of Renierone, 7-Methoxy-l,6-dimethyI-5,8-dihydroisoquinoline-5,8-dione and N-Formyl-l,2-dihydrorenierone, Antimicrobial Metabolites from a Marine Sponge, Reniera sp.

Akinori Kubo; Shinsuke Nakahara; Katsutoshi Inaba; Yoshiyasu Kitahara

Journal ArticleOPEN ACCESS

Synthesis of Renierone, 7-Methoxy-l,6-dimethyI-5,8-dihydroisoquinoline-5,8-dione and N-Formyl-l,2-dihydrorenierone, Antimicrobial Metabolites from a Marine Sponge, Reniera sp.

Chemical and Pharmaceutical Bulletin (1986) 34(10) 4056-4068

DOI: 10.1248/cpb.34.4056

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Abstract

Three isoquinolinequinone antimicrobial metabolites, renierone (3), 7-methoxy-l,6-dimethyl-5,8-dihydroisoquinoline-5,8-dione (4) and N-formyl-1,2-dihydrorenierone (6), isolated from a marine sponge (Reniera sp.), were synthesized. © 1986, The Pharmaceutical Society of Japan. All rights reserved.

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Kubo, A., Nakahara, S., Inaba, K., & Kitahara, Y. (1986). Synthesis of Renierone, 7-Methoxy-l,6-dimethyI-5,8-dihydroisoquinoline-5,8-dione and N-Formyl-l,2-dihydrorenierone, Antimicrobial Metabolites from a Marine Sponge, Reniera sp. Chemical and Pharmaceutical Bulletin, 34(10), 4056–4068. https://doi.org/10.1248/cpb.34.4056

Synthesis of Renierone, 7-Methoxy-l,6-dimethyI-5,8-dihydroisoquinoline-5,8-dione and N-Formyl-l,2-dihydrorenierone, Antimicrobial Metabolites from a Marine Sponge, Reniera sp.

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