Ethyl 2-amino-4-(4-fluorophenyl)-6-methoxy-4H-benzo[h]chromene-3- carboxylate

Abstract

In the title compound, C23H20FNO4, the fluoro-substituted benzene ring is approximately perpendicular to the mean plane of the 4H-benzo[h]chromene ring system [maximum deviation = 0.264 (1) Å], with a dihedral angle of 83.79 (6)°. The pyran ring adopts a flattened boat conformation. The methoxy group is slightly twisted from the attached benzene ring of the 4H-benzo[h]chromene moiety [C - O - C - C = -2.1 (2)°]. An intramolecular N - H⋯O hydrogen bond generates an S(6) ring motif. In the crystal, molecules are linked by N - H⋯O and N - H⋯F hydrogen bonds into a layer parallel to the bc plane. The crystal packing also features C - H⋯π interactions.