Identification of deep-sea-sediment bacteria which produce tetrodotoxin

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Abstract

Forty-nine bacterial strains were isolated from deep-sea sediments. Among them, 22 strains were shown by the tissue culture assay method to produce sodium channel blockers. For some strains, high-performance liquid chromatography analysis confirmed that the blocker was tetrodotoxin. Tetrodotoxin-producing bacteria seem to be widespread in marine sediment.

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Do, H. K., Kogure, K., & Simidu, U. (1990). Identification of deep-sea-sediment bacteria which produce tetrodotoxin. Applied and Environmental Microbiology, 56(4), 1162–1163. https://doi.org/10.1128/aem.56.4.1162-1163.1990

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