Postoperative extradural analgesia following thoracic surgery: A feasibility study

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Abstract

Summary: The feasibility of providing postoperative analgesia using thoracic extradural blockade following thoracotomy has been assessed. Extradural block was produced by intermittent injections of 0.5% bupivacaine with adrenaline 1:200,000 or a continuous infusion of 0.25% or 0.125% bupivacaine. The only toxic symptom was drowsiness which was most frequent after a continuous infusion of 0.25% bupivacaine and with arterial plasma bupivacaine concentrations above 1.5 μg/ml. Arterial hypotension was a troublesome complication with all techniques although stability of arterial pressure was more easily achieved with a continuous infusion technique. However, this produced a high incidence of urinary retention. Practical aspects and effectiveness of providing extradural analgesia in patients following thoracotomy are discussed. © 1975 Macmillan Journals Ltd.

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Griffiths, D. P. G., Diamond, A. W., & J. D. Cameron. (1975). Postoperative extradural analgesia following thoracic surgery: A feasibility study. British Journal of Anaesthesia, 47(1), 48–55. https://doi.org/10.1093/bja/47.1.48

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