Preparation of nitrogen-containing heterocyclic compounds for plant disease control.

Abstract

The invention relates to isoxazolinecarboxamide derivs. of formula I, to processes for prepg. these compds., to compns. comprising these compds., and to the use thereof as biol. active compds., esp. for control of harmful microorganisms in crop protection and in the protection of materials. Compds. of formula I wherein R1 and R2 are independently H, (un)substituted C1-8 alkyl, (un)substituted C2-8 alkenyl, etc.; R1R2 may be taken together to form (un)substituted C3-7 cycloalkyl and C3-7 halocycloalkyl; R3 is H, (un)substituted C1-8 alkyl, C1-8 haloalkyl, (un)substituted C2-8 alkenyl, etc.; R4 is H, OH, CN, etc.; Y is O and S; A is a bond, O, S, SO, etc.; X is H, halo, NO2, CN, etc.; Q1, Q2, Q3, Q4, Q5 and Q6 are independently H, halo, NO2, CN, etc.; and salts and N-oxides, thereof, are claimed. Example compd. II was prepd. by amidation of 3-(3-chloroquinolin-6-yl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid with isopropylamine. The invention compds. were evaluated for their fungicidal activity (some data given). [on SciFinder(R)]