Immunodiagnosis as an aid for early detection of Fasciola gigantica by glutathione S-transferase (GST)

Abstract

In the present study, effort to isolate purified GST from Fasciola gigantica homogenate and its early detection for confirmation of infection has been successful. In this study, immunoprotection studies with GST and antibody titer post-infection has revealed GST to be an immunogenic protein with high sensitivity to detect anti-Fasciola antibody as early as two weeks post-infection in large ruminants. © 2012 Indian Society for Parasitology.