Triterpene, antioxidant, and antimicrobial compounds from Melissa officinalis

Abstract

Six new triterpenes (1-6) and four known compounds have been isolated from dried stems and leaves of Melissa officinalis. The known compounds were identified as quadranoside III, salvianic acid A, rosmarinic acid, and luteolin. The structures of compounds 1-6 were established by analysis of spectroscopic data. Free radical scavenging and antimicrobial activities of the extracts and of rosmarinic acid, the major component, were evaluated. © 2007 American Chemical Society and American Society of Pharmacognosy.