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A party of three: INKT cells in GVHD prevention

Blood (2015) 125(22) 3374-3375
DOI: 10.1182/blood-2015-04-636282
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Abstract

In this issue of Blood, Schneidawind et al1 demonstrate that the adoptive transfer of CD4+ invariant natural killer T (iNKT) cells from third-party mice protects from lethal graft-versus-host disease (GVHD) through expansion of donor regulatory T cells (Tregs) in a murine model of allogeneic hematopoietic cell transplantation (HCT).

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Heine, A., & Brossart, P. (2015). A party of three: INKT cells in GVHD prevention. Blood, 125(22), 3374–3375. https://doi.org/10.1182/blood-2015-04-636282

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