Effects of Shakuyaku-kanzo-to on Painful Nocturnal Leg Cramp Caused by Diabetic Neuropathy.

Abstract

A painful muscle cramp caused by diabetic neuropathy is one of most bothersome symptoms of patients with diabetes mellitus. It happens during night time and causes sleep disturbance. In this communication we report on the clinical usefulness of Shakuyaku-kanzo-to on nocturnal leg cramp. Twelve diabetic patients were treated with 2.5 to 7.5 g/day of Shakuyaku-kanzo-to for 4 weeks. Eight patients were cured of muscle cramp and clinical usefulness was recognized in all patients. In conclusion, Shakuyaku-kanzo-to is very useful in the treatment of patients with muscle cramp caused by diabetic neuropathy. •• OE¾ ‹ß "N"oe"A•a Š³ ŽÒ ‚¨‚ae‚Ñ‚»‚¨‚ae‚Ñ‚» ‚Ì-\ "õOER ‚Å‚ ‚é ‹« ŠEOE^ 'Ï "oe"\ •á ŠQ‚ð'ae ‚· ‚é ŽÒ‚Í '• ‰Á ‚µ‚Ä‚¨‚肵‚Ä‚¨‚è, "ú-{ •l ‚Ì-ñ10%‚ª ‰½ ‚ç ‚©‚̈ق©‚ÌˆÙ•í ‚ð-L‚µ‚Ä‚¢ ‚é ‚AE OE¾ ‚í ‚ê ‚Ä‚¢ ‚é •B‚Ü‚½, •‚-î ‰»‚É"º ‚¢"oe"A•a ‚Ì-• •« • ‡ •¹ •Ç ‚Éoeë Š³ ‚µ‚Ä‚¢ ‚é Š³ ŽÒ•" ‚à '• ‰Á ‚µ‚Ä‚¢ ‚é •B"oe"A•a ‚Ì ŽO 'å • ‡ •¹ •Ç‚Å‚ ‚é, "oe"A•a •«-Ô-OE•Ç, •t •Ç, •_ OEo•á ŠQ ‚Í ‚» ‚ê ‚¼‚ê, Ž¸-Ž¸-¾, •t •s 'S ‚É ‚ae‚é •l •H" §•Í, ‰ó ás "™‚𕵠‚«Š³ ŽÒ‚ÌQOL‚ð '˜ ‚µ ‚-'j ŠQ‚· ‚é ‚¾‚¯ ‚Å‚È ‚-, 'å ‚«‚ȎЉï-â'è ‚AE‚È‚Á‚Ä‚¢ ‚é •B "oe"A•a •« •_ OEo•á ŠQ‚É ‚ae‚é-L 'É•« äC• ‹Øáz •¹, ‚¢ ‚í ‚ä ‚é •u‚± ‚Þ ‚ç ‚ª ‚¦ ‚è•v ‚Í "oe"A•a ‚Ì •a-ð ‚É‚©‚©‚í ‚ç‚¸•‚炸•o OE» ‚· ‚é •B"Á‚É-é ŠÔ‚É•o OE»‚µ, • ‡-°•á ŠQ‚È‚Ç Š³ ŽÒ‚ÌQOL‚ð 'á ‰º‚³ ‚¹ ‚é •Ç•ó ‚̈ê‚Ìˆê ‚Â‚Å‚ ‚é •B ‚± ‚Þ ‚ç ‚ª ‚¦ ‚è ‚Ì "-•Ç‹@•˜ ‚Í-•½•_ OEoŽ²•õ ‚Ì •s ˆÀ 'è ‚È'E•ª ‹É ‚É‚ae‚é ‹Ø"÷‚̈Ù÷‚ÌˆÙ•í Žû•k ‚É ‚ae ‚è"-• ¶ ‚· ‚é ‚AE‚³ ‚ê ‚Ä‚¢ ‚é •B•_ OEoOE´•« Ž¾ Š³ ‚Ì ‚Ý‚È ‚ç ‚¸, OE'•í •l ‚É‚¨‚¢‚É‚¨‚¢ ‚Ä‚à, ‹Ø"÷"ae˜J, 'E•…, "d‰ð Ž¿ˆÙ•í Žž, ‚Ü ‚½, "D•w, "oe"A•a, "A"Å•Ç, ŠÌ •d •Ï ‚È ‚Ç‚Ì Ž¾ Š³, ‚ ‚é Ží ‚Ì-ò •¨ ‚Å ‚à‹N ‚± ‚é ‚± ‚AE ‚ª •ñ •• ‚³ ‚ê ‚Ä‚¢ ‚é1)2)•B "oe"A•a Š³ ŽÒ‚Å‚Í-ñ30%‚AE•‚-¦‚ɉ½ ‚ç ‚©‚Ì-L 'É•« ‹Ø ˆã,-¼ OEà ‰® 'å Šw'aeˆê "à‰È 'aeOEÜ OE¤ ‹ †Žº, ˆ¤ 'm, • §466-8550-¼ OEà ‰® Žs•º ˜a ‹ae'ß •' '¬65 •k1998"N11OEŽ2"ú Žó-• •l