Mauriac syndrome - Is already a history?

Abstract

In 1930 Mauriac described a syndrome characterized by the presence of growth impairment, hepatomegaly, delayed puberty and cushingoid features in patients with poorly controlled type 1 diabetes mellitus (T1DM). At that time, Mauriac syndrome was a common occurrence. This state was maintained even in the fifties and sixties of the last century. The introduction of modern methods of insulin and glucose monitoring decisively reduced the frequency of occurrence of this syndrome. The incidence of Mauriac syndrome decreased dramatically, although it is still being reported. Often in these cases the patients present only some symptoms of this syndrome. The introduction of diagnostic tests allowed to find the genetic basis of these disorders in some of the cases. (Clin Diabetol 2017; 6, 3: 101-104).