Novel glycoinositolphosphosphingolipids, basidiolipids, from Agaricus

Abstract

From the edible mushroom, the basidiomycetes Agaricus bisporus and Agaricus campestris, a novel carbohydratehomologous series of four glyco- inositol-phospho-sphingolipids, designated basidiolipids, was isolated and the constituents purified. The chemical structures of the basidiolipids were elucidated to be: Manpβ1-2inositol1phospbo-ceramide, Galpα-6[Fucpα-2 ]Galpβ-6Manpβ-2inositol1-phospho-ceramide, Galpα-6Galpα-6[Fucpα- 2]Galpβ6Manpβ-2mositol1-phospho-ceramide and Galpα-6Galpα-6Galpα- 6[Fucpα-2]Galpβ-6Manpβ-2inositol1-phosphoceramide. All four glycolipids contained a ceramide which was composed of phytosphingosine and predominantly α-hydroxy-behenic and α-hydroxy-lignoceric acid.