Antibacterial activity of phytogenic silver nanoparticles using domestic herbs plant extract

Abstract

Since the development of the first antibiotic medication, penicillin (1928), a range of antibiotic and antimicrobial agents have been produced and used for both human and industrial applications. However, excess and excessive use of antibiotics has led to a major increase in the number of drug-resistant pathogens. There is a strong demand for novel therapeutic approaches to substitute inefficient antibiotics to address rising microbial multidrug resistance. The invention of nanomaterials as modern antimicrobials creates a new model for antibiotic use in diverse areas. Among the numerous nanoparticles, silver nanoparticles have earned a great deal of interest due to their unique antimicrobial properties. Overall, the results highlight that antibacterial resistance activity of silver nanoparticles from domestic herbs plant of Zingiber officinale var. Extract of rubrum (ZO-AgNPs) and Aloe vera L. Extract (AV-AgNPs) are potentially effective in inhibiting the development of Metichillin Resistant Staphylococcus aureus (MRSA) bacteria. In addition, the formation of AgNPs was observed and characterized by UV-visible spectroscopy at peak ranges 353 - 479 nm, with diameters ranging from 10 - 20 d/nm to 70 - 90 d/nm for both Aloe vera and Red Ginger respectively.