Novobiocin was inactivated by Streptomyces niveus US 2094 in fermentation. The inactivation product was isolated and characterized by NMR and MS as 2″-O-carbamylnovobiocin. The MICs of novobiocin and 2″-O-carbamylnovobiocin were determined for S. niveus strains. © 1991, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
CITATION STYLE
Kuo, M. S., Yurek, D. A., Chirby, D. G., Cialdella, J. I., & Marshall, V. P. (1991). Microbial O-Carbamylation of Novobiocin. The Journal of Antibiotics, 44(10), 1096–1100. https://doi.org/10.7164/antibiotics.44.1096
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