Characterization of the role of calcium in regulating the microtubule-destabilizing activity of MDP25

Abstract

Regulation of cell elongation is important for plant morphogenesis. Many studies have shown that cortical microtubules play crucial roles during cell elongation and that microtubule stability, organization, and dynamics are regulated by microtubule regulatory proteins.1 Recently, we reported that a novel protein from Arabidopsis, termed microtubuledestabilizing protein 25 (MDP25), functions as a negative regulator of hypocotyl cell elongation. MDP25 destabilizes microtubules and exerts its effect on microtubules as a result of transient elevation of cytosolic calcium levels. © 2012 Landes Bioscience.