Study Design: Retrospective cohort study. Objective: Compare the supine vs standing radiographs of patients with adult spinal deformity against ideals defined by healthy standing alignment. Methods: 56 patients with primary sagittal ASD (SRS-Schwab Type N) and 119 asymptomatic volunteers were included. Standing alignment of asymptomatic volunteers was used to calculate PI-based formulas for normative age-adjusted standing PI–LL, L4–S1, and L1–L4. These formulas were applied to the supine and standing alignment of ASD cohort. Analyses were repeated on a cohort of 25 patients with at least 5 degrees of lumbar flexibility (difference between supine and standing lordosis). Results: The asymptomatic cohort yielded the following PI-based formulas: PI–LL = −38.3 +.41*PI +.21*Age, L4–S1 = 45.3–.18*Age, L1–L4 = −3 +.48*PI). PI–LL improved with supine positioning (mean 8.9 ± 18.7°, P 5° corrected on supine imaging (33.9 ± 11.1°, P = 1.000), but L1–L4 did not (23.0 ± 6.2° norm vs 2.2 ± 14.4° standing, P
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Fourman, M. S., Lafage, R., Lovecchio, F., Sheikh Alshabab, B., Shah, S., Punyala, A., … Lafage, V. (2023). How Does Gravity Influence the Distribution of Lordosis in Patients With Sagittal Malalignment? Global Spine Journal, 13(8), 2446–2453. https://doi.org/10.1177/21925682221087467
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