Observation of non-nucleated erythrocytes in the peripheral blood of medaka, Oryzias latipes

Abstract

Summary: The medaka, Oryzias latipes is a useful animal model for the study of vertebrate developmental genetics. Using May-Grünwald-Giemsa stain, we found non-nucleated erythrocytes in the peripheral blood of medaka. Eleven of 50 fish occasionally showed non-nucleated erythrocytes in their peripheral blood. We expect that this observation will be useful in future studies involving screening for hematologic mutants.