Meta-Analysis of Using Both Cohort and Case Control Study

Abstract

This article based on the meta-analysis of using both two measures of strength of association, which are cohort and case control study. Cohort study designs allow for the direct calculation of relative risks from incidences. The situation is more complicated for case-control studies, if meaningful prevalence’s or incidences are not available. Generally speaking, if the risk is greater in exposed, bias term will be greater and the Odds Ratio will overestimate the Relative Risk. However, if incidence in exposed and unexposed is small, bias term will be close to 1.