Total pelvic exenteration for locally advanced colorectal carcinoma

Abstract

Twenty-six patients who Underwent total pelvic exenteration for locally advanced colorectal cancer were studied retrospectively. The operative mortality rate was 8 per cent (two deaths). I patients with stage II primary disease the recurrence rate after curative surgery was three of seven, although the mean suvival time was 58 months and the 5-year survival rate 71 per cent. Patients with stage m primary disease had a shorter mean survivl time regardless of supposed curability (curative 14 months versus non-curative 9 months). Patients with stage IV disease had a mean survival time of 5 months. In patients who underwent curative surgery for recurrent disease the mean survival time was 33 months and 5-year survival rate 25 per cent, although in those receiving non-curative surgery the survival time:was significantly shorter at 10 months (P < 0.05). Total pelvic exenteration is warranted for patients with stage II locally advanced colorectal carcinoma and is an option for those with recurrent carcinoma when performed with curvative intent.