Bioactive isocoumarins and related metabolites from conifer endophytes

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Abstract

Six new [1–4, 7, 9] and two known [6 and 8] metabolites have been isolated from culture filtrates of conifer endophyte strains of Conoplea elegantula. Their structures have been determined by spectroscopic means. Compound 1 was toxic to spruce budworm cells, and both 1 and 3 were toxic to spruce budworm larvae. © 1995, American Chemical Society. All rights reserved.

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Findlay, J. A., Buthelezi, S., Lavoie, R., Pena-Rodriguez, L., & Miller, J. D. (1995). Bioactive isocoumarins and related metabolites from conifer endophytes. Journal of Natural Products, 58(11), 1759–1766. https://doi.org/10.1021/np50125a021

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