"Companion diagnostics": Has their time come and gone?

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Abstract

Rapid development of molecularly targeted drugs requires a "companion diagnostic" that could delay drug development and limit availability of active drugs for relevant patients. Were the negative results from MetMab studies in patients with advanced non-small cell lung cancer due to drug failure or failure of the right companion diagnostic?

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APA

Hirsch, F. R., Bunn, P. A., & Herbst, R. S. (2014). “Companion diagnostics”: Has their time come and gone? Clinical Cancer Research, 20(17), 4422–4424. https://doi.org/10.1158/1078-0432.CCR-14-0932

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