Toxicant-induced oxidative stress in cancer

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Abstract

The article highlighted in this issue is "The Role of Oxidative Stress in Indium Phosphide-Induced Lung Carcinogenesis in Rats" by Barbara C. Gottschling, Robert R. Maronpot, James R. Hailey, Shyamal Peddada, Cindy R. Moomaw, James E. Klaunig, and Abraham Nyska (pp. 28-40). The article integrates a traditional pathologic study of toxicant-induced pulmonary carcinogenesis with an immunohistologic assessment of oxidative stress, thereby determining a potential mechanism of action of a toxicant, specifically indium phosphide.

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Upham, B. L., & Wagner, J. G. (2001). Toxicant-induced oxidative stress in cancer. Toxicological Sciences, 64(1), 1–3. https://doi.org/10.1093/toxsci/64.1.1

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