Abstract
HLA alleles have been associated with psoriasis. Toxin-producing strains of Staphylococcus aureus behave as superantigens, and if present in patients, might play a role in the exacerbation of psoriatic lesions by activating certain V-beta (Vβ) T-lymphocyte subsets. Allele frequencies in 22 patients and 22 controls (alleles determined by DNA/SSP typing) were used to calculate a relative risk of 4.7 (P
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Ajib, R., Janbazian, L., Rahal, E., Matar, G. M., Zaynoun, S., Kibbi, A. G., & Abdelnoor, A. M. (2005). HLA allele associations and V-beta T-lymphocyte expansions in patients with psoriasis, harboring toxin-producing Staphylococcus aureus. Journal of Biomedicine and Biotechnology, 2005(4), 310–315. https://doi.org/10.1155/JBB.2005.310
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