Separation of Micro-Macrocomponent Systems: 149Pm – Nd, 161Tb-Gd, 166Ho-Dy and 177Lu-Yb by Extraction Chromatography

Abstract

149Pm, 161Tb, 166Ho, and 177Lu have advisable nuclear properties to be used in radiotherapy. They can be produced by neutron irradiation of a lanthanide target followed by β- decay and a posterior radiochemical separation of micro-amounts of daughter radionuclide from macro-amounts of the parent target. In order to accomplish the radiochemical separation of micro-macro systems: Nd/149Pm, Gd/161Tb, Dy/166Ho and Yb/177Lu, this work proposes the use of an extraction chromatographic with Ln SPS resin.  Distribution coefficients and separation factors were determined and established the separation conditions of these micro-macro systems.