A multimodal multidomain multilingual medical foundation model for zero shot clinical diagnosis

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Abstract

Radiology images are one of the most commonly used in daily clinical diagnosis. Typically, clinical diagnosis using radiology images involves disease reporting and classification, where the former is a multimodal task whereby textual reports are generated to describe clinical findings in images, as are common in various domains, e.g., chest X-ray or computed tomography. Existing approaches are mainly supervised, the quality of which heavily depends on the volume and quality of available labeled data. However, for rarer or more novel diseases, enrolling patients to collect data is both time-consuming and expensive. For non-English languages, sufficient quantities of labeled data are typically not available. We propose the Multimodal Multidomain Multilingual Foundation Model. It is useful for rare diseases and non-English languages, where the labeled data are frequently much more scarce, and may even be absent. Our approach achieves encouraging performances on nine datasets, including 2 infectious and 14 non-infectious diseases.

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Liu, F., Li, Z., Yin, Q., Huang, J., Luo, J., Thakur, A., … Clifton, D. A. (2025). A multimodal multidomain multilingual medical foundation model for zero shot clinical diagnosis. Npj Digital Medicine, 8(1). https://doi.org/10.1038/s41746-024-01339-7

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