The histomorphometric analysis of maxillary sinus lift elevation using the synthetic hydroxyapatite and tricalcium phosphate grafting materials

Abstract

The aim of the study was to conduct an evaluation of the success of implants inserted into the distal maxilla augmented via the lateral sinus lift method using a combination of synthetic alloplastic hydroxyapatite and β-tricalcium phosphate materials. The solubility of PORESORB-TCP in body fluids leads (due to TCP dissolution) to their hyper-saturation with Ca2+ and P ions, which gradually reprecipitate as CaP. OssaBase-HA has been shown to evince osteoconductive properties. The aim was to take advantage of the synergistic osteoconduction potential of the hydroxylapatite OssaBase-HA and β-tricalcium phosphate PORESORB-TCP materials. We selected a ratio of the two materials of 3:2 for experimentation purposes. The histological findings clearly indicated that, concerning the histological sample, the area of the original bone was 21.4 % and the area of augmented tissue occupied 78.6 %. The proportion of bone of the patients’ hard tissue was 68.3 % compared to 43.9 % of bone with the new augmented tissue. The volume of the augmentation material in the augmented tissue was determined at 45.6 %. The amount of PORESORB-TCP was 34.1 % of the augmentation material, and the amount of OssaBase-HA was 11.6 % of the augmentation material. Our study thus confirmed the osteoconductive properties of the hydroxylapatite OssaBase-HA and β-tricalcium phosphate PORESORB-TCP materials and demonstrated the osteoconduction of a 3:2 mixture of the two materials, thus proving the synergy of their respective properties.