Usefulness of endoscopic biliary drainage for hepatocellular carcinoma associated with obstructive jaundice

Abstract

We investigated the efficacy of endoscopic biliary drainage for hepatocellular carcinoma with obstructive jaundice due to bile duct invasion or retraction. We observed 20 cases of hepatocellular carcinoma with obstruc[1]tive jaundice from January 2008 to March 2023 and included 16 men and 4 women with an average age of 75 ±8 years. The extent of portal vein invasion was Vp0/Vp2/Vp3 (13/3/4 cases), and stent insertion occurred in 16 cases. Those who underwent stent insertion had a significantly longer overall survival (OS) (p < 0.001). There was no significant difference in OS between those who received PS (n = 7) and SEMS (n = 9) (p = 0.218). A significant difference was observed in the total bilirubin levels before and after endoscopic biliary drainage (p = 0.001). Endoscopic biliary drainage is useful for obstructive jaundice in advanced hepatocellular carcinoma with poor liver function and should be considered based on the patientʼs general condition.