Relationship between aerobic capacity and cardiovascular disease risk factors in Thai men and women with normolipidemia and dyslipidemia

Abstract

[Purpose] This research aimed to investigate the relationship between aerobic capacity (VO2,peak) and cardiovascular risk factors in normolipidemic and dyslipidemic Thai men and women. [Subjects and Methods] We recruited 104 dyslipidemic and 100 healthy participants. Fasting blood samples were analyzed for lipid and blood glucose levels. Anthropometry, blood pressure, and body composition were measured before exercise. Each subject underwent exercise testing to determine VO2, peak. Heart rate (HR) was recorded throughout the exercise test. [Results] Dyslipidemic participants had a lower VO2, peak than normolipidemic participants (p<0.01). In normolipidemic male participants, VO2, peak was positively correlated with high density lipoprotein cholesterol (HDL-C) levels and negatively correlated with low density lipoprotein cholesterol (LDL-C) levels and triglycerides to HDL-cholesterol (TG/HDL-C) ratios; in females, VO2, peak was negatively correlated with age, total cholesterol, and LDL-C. In dyslipidemic males, VO2, peak was positively correlated with HDL-C levels and negatively correlated with age, LDL-C and TG levels, and percent body fat; in females, VO2, peak was positively correlated with resting HR and heart rate recovery and negatively correlated with age, TG/HDL-C, and waist circumference. [Conclusion] There was a relationship between aerobic capacity and cardiovascular disease risk factors in both normolipidemic and dyslipidemic participants. This relationship was affected by gender.