ANALISIS EFEKTIVITAS BIAYA PENGOBATAN DEMAM BERDARAH DENGUE MENGGUNAKAN TERAPI SUPORTIF IMUNOMODULATOR DAN SEDIAAN YANG MENGANDUNG EKSTRAK DAUN JAMBU BIJI

Abstract

Dengue Hemorrhagic Fever (DHF) is a serious disease caused by the dengue virus infections. immunomodulators is widely used as a supportive treatment for dengue fever patients. But along with the progress of herbal medicine, developed other drugs containing guava leaves extract can stimulate the formation of platelets in patients with dengue hemorrhagic fever but drug prices are still quite expensive.This study aimed to determine the cost effectiveness of immunomodulator and herbal  medicine containing guava leaves extract in  patients  with dengue hemorrhagic fever. observasional analitical study with  retrospective approach. the medical records of  patients treated in Baitul Nisa and Baitul Athfal grade 3 Sultan Agung Islamic Hospital between August 2014 and August 2016 that meeting the inclusion criteria. ACER (Average Cost Effectiveness Ratio) was  used to  evaluate the daily  cost for  treatment. the value ACER for patients treated with immunomodulator was Rp 334.073, - / day with 4.78 day duration of  hospitalization.  while the value of the ACER for patients taking  herbal  medicine containing guava leaves extract was of Rp 343.894, - / day with 5 days  duration of  hospitalisation. There was  no  significant  difference in cost effectiveness between  patients  treated  with immunomodulator and herbal  medicine containing extract of guava leaves (p> 0.05). There was a difference in cost effectiveness between immunomodulator and herbal medicine containing guava leaves extract.