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One-pot synthesis of simple alkaloids: 2,3-Polymethylene-4(3H)- quinazolinones, luotonin A, tryptanthrin, and rutaecarpine

Chemical and Pharmaceutical Bulletin (2008) 56(4) 607-609
DOI: 10.1248/cpb.56.607
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Abstract

One-pot synthesis of various 2,3-polymethylene-4(3H)-quinazolinones from anthranilic acid, corresponding lactam and SOCl2 is described, which can be applicable to the synthesis of simple 4(3H)-quinazolinone-derived alkaloids, such as luotonin A, tryptanthrin, and rutaecarpine. © 2008 Pharmaceutical Society of Japan.

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Jahng, K. C., Kim, S. I., Kim, D. H., Seo, C. S., Son, J. K., Lee, S. H., … Jahng, Y. (2008). One-pot synthesis of simple alkaloids: 2,3-Polymethylene-4(3H)- quinazolinones, luotonin A, tryptanthrin, and rutaecarpine. Chemical and Pharmaceutical Bulletin, 56(4), 607–609. https://doi.org/10.1248/cpb.56.607

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