Hypoglycemic effect of leaf extract of Fimbristylis miliacea in mice model

Abstract

Hypoglycemic effect of methanol extract of leaf of Fimbristylis miliacea was examined in mice model. Standard drug glibenclamide reduced fasting blood glucose concentration by 46.69% after 3 h while extract at 400 mg/kg showed 36.92% reduction after same time span. Therefore, it can be concluded that the plant extract is expected to contain phytoconstituent(s) with potential hypoglycemic effect in dextrose-induced hyperglycemic mouse model.