Circulating tumor DNA monitoring detects minimal residual disease and predicts outcomes in patients with esophageal adenocarcinoma or squamous cell carcinoma after esophagectomy

  • Hu Q
  • Kimura Y
  • Ikeda S
  • et al.
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Abstract

Circulating tumor DNA (ctDNA) monitoring shows promise for detecting minimal residual disease (MRD) and predicting prognosis in various cancers, but its role in esophageal cancer (EC) post-esophagectomy is unclear. This study evaluated ctDNA for detecting MRD and predicting outcomes in EC patients.

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Hu, Q., Kimura, Y., Ikeda, S., Tanaka, Y., Nakanoko, T., Ota, M., … Oki, E. (2025). Circulating tumor DNA monitoring detects minimal residual disease and predicts outcomes in patients with esophageal adenocarcinoma or squamous cell carcinoma after esophagectomy. BJC Reports, 3(1). https://doi.org/10.1038/s44276-025-00158-x

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