The Ruminant Telomere-to-Telomere (RT2T) Consortium

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Abstract

Telomere-to-telomere (T2T) assemblies reveal new insights into the structure and function of the previously ‘invisible’ parts of the genome and allow comparative analyses of complete genomes across entire clades. We present here an open collaborative effort, termed the ‘Ruminant T2T Consortium’ (RT2T), that aims to generate complete diploid assemblies for numerous species of the Artiodactyla suborder Ruminantia to examine chromosomal evolution in the context of natural selection and domestication of species used as livestock.

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Kalbfleisch, T. S., McKay, S. D., Murdoch, B. M., Adelson, D. L., Almansa-Villa, D., Becker, G., … Rosen, B. D. (2024). The Ruminant Telomere-to-Telomere (RT2T) Consortium. Nature Genetics, 56(8), 1566–1573. https://doi.org/10.1038/s41588-024-01835-2

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