Lung function estimation from a monosyllabic voice segment captured using smartphones

Abstract

Chronic respiratory diseases refer to a group of lung diseases that affect the airways and cause difficulty in breathing. Respiratory diseases are one of the leading causes of death and negatively impact the patients' quality of life. Early detection and regular monitoring of lung functions might reduce the risk of death; however, lung function assessment requires the active supervision of a medical professional in a clinical setting. To make lung function tests more accessible and ubiquitous, researchers started leveraging mobile devices, which still require active supervision and demand extraneous effort from the user. In this work, we propose a convenient mobile-based approach that uses a monosyllabic voice segment called 'A-vowel' sound or 'Aaaa...' sound to estimate lung function. We conducted two studies (a lab study and an in-clinic study) with 201 participants to develop a detection model detecting 'A-vowel' sound from other acoustic events and a prediction model to estimate the lung function using the detected A-vowel sound. Our study shows that A-vowel sounds can be detected with 93% accuracy, and A-vowel sounds can estimate lung functions with 7.4-11.35% mean absolute error. We also conducted a validation study with 10 participants in a noisy environment and able to detect A-vowel segments with 71% F1-Score. Our results show auspicious directions to expand the horizon of mobile-based lung assessment.