Breast Cancer Arising from a Suspected Fibroadenoma during Pregnancy: A Case Report and Review of Literature

Abstract

Introduction: Fibroadenomas are the most common benign neoplastic lesion of the breast. These hormone-sensitive tumors can grow rapidly under the influence of pregnancy hormones. Although rare, malignant transformation of these lesions has been reported. The risk of the standard treatment regimen on the fetus makes the PABC (Pregnancy-Associated Breast Cancer) a challenging task for clinicians. Overall treatment is based on guidelines for the general population with some variations to decrease the risk of fetal damage as much as possible.