PhenomiR: A knowledgebase for microRNA expression in diseases and biological processes

Abstract

In recent years, microRNAs (miRNAs) have been shown to play important roles in physiological as well as malignant processes. The PhenomiR database (http://mips.helmholtzmuenchen. de/phenomir) provides data from 542 studies that investigate deregulation of microRNA expression in diseases and biological processes as a systematic, manually curated resource. Using the PhenomiR dataset, we could demonstrate that depending on disease type, integration of independent information from cell culture studies contrast with conclusions drawn from patient studies. © 2010 Ruepp et al., licensee BioMed Central Ltd.